Epidemiological Study of Fabry Disease in Taiwan Young Stroke Patients

Chiayi Christian Hospital

Status: Unknown

Conditions: Fabry Disease

Treatments: Genetic: GLA gene

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03596398

105028

Details and patient eligibility

About

Epidemiological Study of Fabry Disease in Taiwan Young Stroke Patients

Full description

This is a cross-sectional, population-based study. No randomization procedure will be executed in this study. Approximately 1000 subjects over a 36-month period. The aim of this screening study is to identify the Fabry disease as the cause in patients with young stroke.

To measure the level of α-Gal A activity, male subjects will initially provide a DBS sample and female subjects will start with a test by whole blood sample.

The prevalence of Fabry disease among patients with young stroke will be estimated by a confirmative diagnosis in gene testing.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 20 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 20 or over
• Patients aged under 56 years old, not included 56
• Patients with acute stroke
• Patients and/or their legal representatives are willing to provide written informed consent

Exclusion criteria

• Patients with a confirmed diagnosis of Fabry disease

Trial design

1,000 participants in 1 patient group

Young stroke

Description:

Patients with acute stroke aged 20 or over, and under 56 years old (Not included 56) .

Treatment:

Genetic: GLA gene