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Epidemiological Study of Intestinal Colonization With Staphylococcus Aureus (DigeSTAPH)

C

Centre Hospitalier Universitaire de Saint Etienne

Status

Completed

Conditions

Staphylococcus Aureus

Treatments

Procedure: Nasal and rectal bacterial samples

Study type

Observational

Funder types

Other

Identifiers

NCT02547272
1208087
2012-A01182-41 (Other Identifier)

Details and patient eligibility

About

Nasal colonization with S. aureus is a risk factor for infection with this bacterium. A methodologically well conducted study of S. aureus bacteremia showed that 80% of S. aureus bacteremia with are due to the strain isolated in the nasal level. However, as part of a study coordinated by the CHU of Saint-Etienne, less than 50% of infections in prosthetic orthopedic devices have been linked to nasal carriage . Outside of exogenous infections, intestinal colonization with S. aureus could be an alternative source of endogenous infections with the waning of orthopedic surgery. In the general population, considering that about one third of the subjects were colonized with S. aureus nasal level and 1 in 5 in the intestine However the proportion of exclusive intestinal porting is not well known .

This study will analyze, among ICU patients, porting S. aureus nasal and rectal level. It will better clarify the relationship between nasal and rectal ports and the risk of developing an infection.

Full description

The adult patients hospitalized in intensive care at the University Hospital of Saint-Etienne have a multiresistant bacteria porting screening at the nose and rectum at admission and then once a week. These samples will be carried unchanged way for the study but will also be a research S Aureus

Enrollment

400 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients hospitalized in intensive care and benefiting from a screening multiresistant bacteria in nasal and rectal level under routine care

Exclusion criteria

  • refusal of the patient's family

Trial design

400 participants in 1 patient group

Nasal and rectal samples
Description:
ICU patients with nasal and rectal bacterial samples for the presence of S Aureus
Treatment:
Procedure: Nasal and rectal bacterial samples

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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