Epidemiological Study of Out-of-hospital Cardiac Arrest in Guangzhou

Sun Yat-sen University

Status: Active, not recruiting

Conditions: Sudden Cardiac Death; Cardiac Arrest

Treatments: Diagnostic Test: "cardiac arrest" and "sudden death"

Study type: Observational

Funder types: Other

Identifiers

NCT06448156

MR-44-24-003181

Details and patient eligibility

About

Aim This was a population-based retrospective cohort study of OHCA. This study intends to retrospectively analyze the data of pre-hospital emergency system in Guangzhou for 10 years, explore the incidence trend of OHCA in Guangzhou for 10 years; Through further analysis, we try to explore the time distribution characteristics of OHCA in order to understand the epidemiological characteristics and rules of OHCA in super large cities in southern China.

Methods The pre-hospital traffic data in the main urban area of Guangzhou Emergency Medical Command Center database from 2011 to 2020 were collected. The cases diagnosed as "cardiac arrest" and "sudden death" were screened, and the cases with non-cardiac causes in the diagnosis were deleted. The crude incidence rate and age-standardized incidence rate of OHCA were calculated. Joinpoint software was used to calculate the changing nodes in the OHCA incidence trend, and the AnnualPercent Change (APC) and Average AnnualPercent Change (Average AnnualPercent Change, APC) of OHCA incidence were calculated. AAPC). The OHCA data were grouped according to the six main urban areas, and the crude incidence rate, ASIR and changing trend of the six main urban areas were calculated. The data of OHCA were grouped by age, and the crude incidence rate, ASIR and changing trend of each age group were calculated. The data information was divided into groups according to 24 hours a day, 7 days a week, and four seasons. The number of OHCA cases in different time periods was statistically described. The data were imported into SPSS 26.0 for analysis, and Mann-Kendall test was used to evaluate the statistical significance of the time trend. Time rhythm variability was tested for mean distribution using chi-square goodness of fit test.

Enrollment: 44,375 patients

Sex: All

Ages: Under 120 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Cases in the database with a secondary diagnosis containing the diagnostic keywords "cardiac arrest" and "sudden death"

Exclusion criteria

1. cases where the diagnosis of "cardiac arrest" and "sudden death" includes a diagnosis of a non-cardiac cause such as asphyxiation, suicide, drowning, advanced cancer, trauma, shock, poisoning, cerebral vascular accident, etc;
2. cases with duplicate records of sex, age, time of call, pick-up address and initial diagnosis

Trial design

44,375 participants in 8 patient groups

0-19 years age group

Treatment:

Diagnostic Test: "cardiac arrest" and "sudden death"

20-29 years age group

Treatment:

Diagnostic Test: "cardiac arrest" and "sudden death"

30-39 years age group

Treatment:

Diagnostic Test: "cardiac arrest" and "sudden death"

40 to 49 age group

Treatment:

Diagnostic Test: "cardiac arrest" and "sudden death"

50 to 59 age group

Treatment:

Diagnostic Test: "cardiac arrest" and "sudden death"

60 to 69 age group

Treatment:

Diagnostic Test: "cardiac arrest" and "sudden death"

70 to 79 age group

Treatment:

Diagnostic Test: "cardiac arrest" and "sudden death"

80+age group

Description:

Age group greater than or equal to 80 years

Treatment:

Diagnostic Test: "cardiac arrest" and "sudden death"