Epidemiological Study on the Relationship Between Respiratory Health and Air Pollution From Industrial Sources (ELISABET)

University Hospital, Lille

Status: Completed

Conditions: Hypertension; Dyslipidemias; Diabetes Mellitus; Pulmonary Disease, Chronic Obstructive; Airway Obstruction

Treatments: Other: heteroevaluation scale by a nurse or doctor

Study type: Observational

Funder types: Other

Identifiers

NCT02490553

2010-A00065-34 (Other Identifier)

2009_32/1003

Details and patient eligibility

About

The ELISABET STUDY is across sectional Survey on a representative sample of two urban area conduct on a representative sample. The main objective of the project is to compare the prevalence of the obstructive ventilatory disorders (OVD) in the Urban Community of Dunkirk touched by the industrial pollution in relation to the one recovered in the Urban Community of Lille (CUDL) less industrialized.

Full description

Airflow obstruction include Pulmonary Disease, Chronic Obstruction and asthma. Identification of Airflow obstruction is through Functional Tests Lung. In the 1950s, high pollution levels were associated with increased mortality. Despite a reduction of air pollution, it has been established that pollution peaks have short-term effects on acute respiratory episodes. The Urban Community of Dunkirk (CUD) focuses many large pollutant emitters. The long term effects of industrial pollution on TVO are unknown.

The main objective of the project is to compare the prevalence of Airflow obstruction in the Urban Community of Dunkirk affected by industrial pollution compared to that found in the Urban Community of Lille (CUDL) less industrialized. Secondary objectives are: 1) To assess the relationship between air pollution from industrial and biological markers, particularly the plasma concentrations of heavy metals 2) To assess the prevalence of TVO general population in French populations 3) Establish a baseline epidemiological and biological bank.

Enrollment: 3,276 patients

Sex: All

Ages: 40 to 64 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• had lived for at least 5 years in the same city or its surrounding urban area (either Lille or Dunkirk) in the northern of France
• Agreed to participate and signed contentment

Exclusion criteria

• The detainees
• People under legal protection
• Individuals unable to consent

Trial design

3,276 participants in 2 patient groups

Dunkirk area

Description:

Representative sample of Dunkirk and the surrounding urban area (of \~200 000inhabitants).Dunkirk area is characterize by high emission of industrial air pollutant

Treatment:

Other: heteroevaluation scale by a nurse or doctor

Lille area

Description:

Representative sample of Lille and the surrounding urban area (of \~1 million inhabitants, the fourth urban area in France)

Treatment:

Other: heteroevaluation scale by a nurse or doctor