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Epidemiology of Abnormal Vaginal Discharge During Pregnancy

A

Assiut University

Status

Unknown

Conditions

Vaginal Infection

Treatments

Diagnostic Test: Vaginal swab

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Vaginitis among women of childbearing age is well acknowledged as a public health concern due to its high occurrence. Vulvovaginitis is a disorder of the vulva and/or vagina caused by infection, inflammation, or changes in the flora.

There are many types of infections that affect the vagina, the most common three types of infection: bacterial vaginosis, trichomoniasis, and candidiasis. Bacterial vaginosis is the most common vaginal infection in women of reproductive age causing thin and milky vaginal discharge with a fishy odor. Trichomoniasis causes a frothy, greenish-yellow discharge with a foul smell.

Vaginal Candidiasis is one of the most common fungal infections of the female genital tract and the second most common vaginal infection affecting women of reproductive age (after the bacterial infection worldwide. It affects more than 75% of women at least once in their lifetime, with approximately 50% of them also suffering a single recurrence.

About 75% of patients suffering from candidiasis are asymptomatic, but it may be symptomatic with clinical picture characterized by itching, vaginal pain, vulvar burning sensation, dyspareunia, dysuria and mildly unpleasant odor, erythema and vulvar edema, white-yellowish plaques on the walls of the vagina and cervix and cheesy vaginal discharge. The risk of vulvo-vaginal candidiasis increases by 30% during pregnancy also in pregnancy, the presence of vaginitis is related to abortion, intrauterine infection, fetal growth retardation, premature rupture of membranes, preterm birth, low birth weight, puerperal infection, and other adverse pregnancy outcomes.

Enrollment

164 estimated patients

Sex

Female

Ages

19 to 40 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • At any gestational age
  • Age of patient: 19-40

Exclusion criteria

  • Women in labor
  • Women with current vaginal bleeding
  • Women with current preterm rupture of membrane
  • Women immunocompromised women
  • Women patients who refused to participate in the study

Trial design

164 participants in 2 patient groups

Pregnant women with abnormal vaginal discharge
Treatment:
Diagnostic Test: Vaginal swab
Pregnant women without abnormal vaginal discharge
Treatment:
Diagnostic Test: Vaginal swab

Trial contacts and locations

1

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Central trial contact

Doaa Makarem, MSc; Ahmed Alaa Youssef, MD

Data sourced from clinicaltrials.gov

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