Epidemiology of Bacteremia at Two Tertiary ICUs in Switzerland

Insel Gruppe AG, University Hospital Bern

Status: Completed

Conditions: Bacteremia

Treatments: Diagnostic Test: Blood Culture

Study type: Observational

Funder types: Other

Identifiers

NCT05236283

2021-02302

Details and patient eligibility

About

The objectives of the retrospective cohort study is to describe the actual current practice of antibiotic treatment duration for bloodstream infections in critically ill patients at two tertiary hospitals (ICU Inselspital Bern and ICU CHUV Lausanne), to examine patient, pathogen and infectious syndrome factors associated with selection of shortened treatment duration, and to describe the expected time course of clinical resolution among bacteremic patients.

Enrollment: 395 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patient has a positive blood culture with a pathogenic organism Patient is critically ill at the time the blood culture was collected as defined by the following:

1. was treated at the ICU/IMC at the time of blood culture collection;
2. or has been admitted to ICU/IMC in the 48 hours after blood culture collection

Exclusion criteria

1. Patient has a single positive blood culture with a common contaminant organism:

   • coagulase negative staphylococci;
   • Bacillus spp.;
   • Corynebacterium spp.;
   • Propionibacterium spp.;
   • Aerococcus spp.;
   • Micrococcus spp.

2. Explicit documentation that the patient does not want to participate in any study

Trial design

395 participants in 2 patient groups

Bern ICU

Treatment:

Diagnostic Test: Blood Culture

Lausanne ICU

Treatment:

Diagnostic Test: Blood Culture