Epidemiology of Resistant Microbial Strains Among Different Groups of People (Healthy, Infected and Exposed to Animals) (ABRESIST)

University of Tartu

Status: Unknown

Conditions: ESBL Producing K.Pneumoniae; Vancomycin (Glycopeptide) Resistant Enterococcus (VRE); ESBL Producing E.Coli; Methicillin Resistant Staphylococcus Aureus (MRSA); Carbapenem Resistant P.Aeruginosa; Multidrug Resistant P.Aeruginosa

Study type: Observational

Funder types: Other

Identifiers

NCT03343119

SLOTI12038T

Details and patient eligibility

About

This study investigates carriage rate and risk factors for acquiring multiresistant bacteria (ESBL producing E.coli and K.pneumoniae, carbapenem-resistant and multidrug resistant P.aeruginosa, MRSA and VRE) in hospitalised patients and healthy volunteers.

Enrollment: 708 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

I group Hospitalised patients Inclusion Criteria

• MDR bacteria (listed above) isolated from clinical specimen
• hospitalisation to the Tartu University Hospital or North Estonia Medical Centre or West Tallinn Central Hospital or East-Tallinn Central Hospital or The Hospital of Reconstructive Surgery

II group Healthy volunteers Inclusion Criteria

• age >6 months
• have not received any antibacterial treatment in previous 3 months
• have not been hospitalised in previous 3 months

III group Dog owners Inclusion Criteria

• age >6 months
• have not received any antibacterial treatment in previous 3 months
• have not been hospitalised in previous 3 months
• owning a dog

IV group veterinarians Inclusion Criteria

• have not received any antibacterial treatment in previous 3 months
• have not been hospitaliZed in previous 3 months
• working as a veterinarian

V group pig farmers Inclusion Criteria

• have not received any antibacterial treatment in previous 3 months
• have not been hospitalized in previous 3 months
• occupation as a pig farmer

Trial design

708 participants in 5 patient groups

Hospitalised patients

Description:

No intervention

Healthy volunteers

Description:

No intervention

Dog owners (healthy volunteers)

Description:

No intervention

Veterinarians (healthy volunteers)

Description:

No intervention

Pig farmers (healthy volunteers)

Description:

No intervention