Epidermoid Cancer Development in Esophageal Achalasia

Sandro Mattioli

Status: Enrolling

Conditions: Achalasia; Epidermoid Carcinoma

Treatments: Diagnostic Test: Clinical instrumental examinations

Study type: Observational

Funder types: Other

Identifiers

NCT03546998

Epidermoid cancer in achalasia

Details and patient eligibility

About

Esophageal achalasia is a precancerous condition for epidermoid carcinoma; incidence and risk factors for cancer development are not defined. Incidence and risk factors for epidermoid carcinoma development in achalasia patients were investigated.

Full description

In order to define incidence and risk factors for epidermoid carcinoma 681 patients affected by esophageal achalasia observed since 1973 were followed up with no time limits according to a prospective follow-up protocol. The local institutional review board approved using the database from the division of thoracic surgery for research purposes. Clinical, radiological and endoscopic data of achalasia patients were collected and analyzed.

Enrollment: 681 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis of primary esophageal achalasia achieved by means of radiology, endoscopy and manometry

Exclusion criteria

• pseudoachalasia