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Epidural Analgesia and Delivery of Second Twin

A

Abdelrady S Ibrahim, MD

Status

Completed

Conditions

Labor Pain
Epidural
Analgesia

Treatments

Drug: Bupivacaine-fentanyl

Study type

Observational

Funder types

Other

Identifiers

NCT04608006
Assiut Universitr (Other Identifier)
IRB0000871247
Ain Shams University

Details and patient eligibility

About

Over an 8-year period, 124 twin pregnancies at gestational age ≥32 weeks with both twins presenting as a vertex and eligible for vaginal delivery were reviewed. Excluded were patients with the following intrapartum factors which may affect mode of delivery of second twin: 1. Presentation of the 2nd twin: breech or other than vertex; 2. Monochorionic twins; 3. Induction of labour; 4. difference in foetal weight between twin B and twin A ≥25%. The chi-square statistic was used to compare differences in the incidence of retained second twin between the groups.

Full description

The investigators conducted this prospective study in women with twins pregnancy planned for trial of vaginal delivery and gave birth between January 2014 and December 2019, in the Department of obstetrics and Gynaecology of the Sabah Maternity Hospital, Sabah Specialized Area, Kuwait. The Sabah Maternity Hospital is a tertiary care hospital for the country of Kuwait with approximately 12500 deliveries per year. The study protocol was approved by the Ethics Committee.

Enrollment

124 patients

Sex

Female

Ages

16 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

.gestational age of 32 weeks, determined by an early ultrasound performed in the second trimester or certain last menstrual period; (2) both twins viable; (3) eligibility for vaginal delivery as defined by twin A being cephalic; and (4) no previous cesarean section.

Exclusion criteria

  • underwent an elective or repeat cesarean section
  • presentation of twin B at delivery other than cephalic (breech, oblique or transverse presentation
  • induction of labour
  • the difference in foetal weight between twin B and twin A at delivery ≥25% .Neonates were excluded if one was stillborn or had major congenital malformations.

Trial design

124 participants in 3 patient groups

Vaginal Delivery
Description:
Delivered both twins vaginally
Treatment:
Drug: Bupivacaine-fentanyl
C-Section Delivery
Description:
Delivered both twins by Cesarean Section
Treatment:
Drug: Bupivacaine-fentanyl
Vaginal/C-Section Delivery
Description:
Delivery first twin vaginally and second twin By C-Section.
Treatment:
Drug: Bupivacaine-fentanyl

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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