Epigenetic Changes in Head and Neck Cancer

Aalborg University Hospital

Status: Completed

Conditions: Squamous Cell Carcinoma; Head and Neck Neoplasms; Head and Neck Cancer; Head and Neck Squamous Cell Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT04260074

N-20190047

Details and patient eligibility

About

With this study, the investigators will investigate the epigenetic changes, which may contribute to the development of head and neck squamous cell carcinomas.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Cancer group:

Inclusion Criteria :

• Written informed consent
• Histologically confirmed oral squamous cell carcinoma

Exclusion Criteria:

• History of cancer
• Uncontrolled comorbidity

Control group:

Inclusion Criteria :

• Written informed consent
• Normal buccal mucosal surface.
• Normal ENT-examination

Exclusion Criteria:

• History of cancer
• Uncontrolled comorbidity

Trial design

40 participants in 2 patient groups

Oral Cancer group

Description:

20 consecutive patients with oral squamous cell carcinoma referred to the Department of Otolaryngology - Head and Neck Surgery

Healthy oral mucosa group

Description:

20 controls with normal buccal mucosa upon examination.