Epigenetic Optimization Through Biofrequency Nutrition

Universidad de Almeria

Status: Not yet enrolling

Conditions: Epigenetic; Nutrition Habits; Biomarkers / Hair

Treatments: Behavioral: Personalized Nutritional Follow-Up

Study type: Interventional

Funder types: Other

Identifiers

NCT07093242

UALBIO2025/010

Details and patient eligibility

About

Biomarker-based nutrition has demonstrated superior efficacy compared to population-level approaches in improving health outcomes. Biofrequency analysis, a non-invasive technique based on the detection of electromagnetic vibrational patterns in hair follicles, offers a promising avenue for rapid functional assessment of nutritional status and epigenetic signals without reliance on blood or urine sampling. First, to evaluate the effect of a 90-day biofrequency-guided nutritional intervention on functional epigenetic status, as reflected in changes in the optimization report generated by the S-Drive system; second, to assess changes in adherence to the Mediterranean diet, anthropometric indicators, movement behaviors, and psychological well-being. Methods: In this randomized controlled trial, adults from a Sport Team from Region of Murcia (Spain) will be allocated to an experimental group receiving individualized lifestyle recommendations based on S-Drive biofrequency analysis and to a control group with no intervention. Participants in the experimental arm will apply tailored dietary guidance over 90 days. Conclusion: This study will generate foundational evidence on the utility of biofrequency technology for precision nutrition. If positive, the findings may inform scalable, low-risk strategies for personalized dietary interventions in preventive and community health settings.

Enrollment: 150 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age between 18 and 65 years.
• Active member of a registered athletics club.
• Willingness to provide a hair sample for genetic analysis.
• Ability to understand and sign the informed consent form.
• Commitment to complete the nutritional follow-up (for the intervention group) and to respond to pre- and post-intervention questionnaires.

Exclusion criteria

• Prior medical diagnosis of a genetic disorder affecting nutritional metabolism.
• Current use of nutritional supplements or special diets prescribed for medical reasons.
• Participation in another clinical or nutritional study during the intervention period.
• Pregnancy or breastfeeding at the time of enrollment.
• Inability to attend baseline or post-intervention assessments.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

150 participants in 2 patient groups

Experimental Group - Nutritional Follow-Up

Experimental group

Description:

Participants in this group receive a genetic hair analysis and a personalized nutritional follow-up based on the results. The aim is to assess whether the nutritional intervention modifies relevant genetic or biochemical markers after the intervention period.

Treatment:

Behavioral: Personalized Nutritional Follow-Up

Control Group - Results Only

No Intervention group

Description:

Participants in this group receive a genetic hair analysis and are provided with the results only, without any nutritional follow-up. This group serves as a comparison to evaluate the effect of the nutritional intervention in the experimental group.