Epileptogenic Zone's Cartography by Quantification of EEG's Signal and Intracerebral Stimulation. (EPISTIM)

Grenoble Alpes University Hospital Center (CHU)

Status

Unknown

Conditions

Epilepsy

Treatments

Other: Functional stereotaxic exploration

Study type

Interventional

Funder types

Other

Identifiers

NCT02844374

38RC14.079

Details and patient eligibility

About

Epilepsy is a devastating chronic disease due to multiple causes that affect close to 50% of the world's population.

Although effective, epilepsy surgery fails in many cases, the percentage of patients free from crisis on a long term (≥ 5 years) varies from 27% to 66% according to the kind of epilepsy.

It is in this context that EPISTIM is interesting, and its aims isb a better electrophysiology delimiting of cortical networks that imply the genesis of seizures with the aim to improove surgery results.

This study will rely on the intracerebral records and on corticales electrical stimulation as they are currently routinely used by epileptic patients candidates for surgery.

Enrollment

45 estimated patients

Sex

All

Ages

5 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria :

Patient from 5 to 65 years (L1121-7 L1122 2 CSP), including legally protected or unable to give his consent (L1121-8 CSP).
Written approval of inclusion in the study from the patient or his legal representative.
Patients with partial Epilepsy Drug Resistant , justifying a SEEG exploration.

Exclusion Criteria :

Patient under 5 years.
Patient over 65 years.
Pregnant or breastfeeeding women (L1121-5 CSP).
Patient deprived of liberty as a result of a judicial or administrative decision (L1121-6 CSP).
Patients over 18 years unable to give their free consent and not subject to a legal protection order.