EQQUAL-NM for the Promotion of Smoking Cessation in Sexual and Gender Minority Young Adults in New Mexico

Fred Hutchinson Cancer Center (FHCC)

Status: Withdrawn

Conditions: Cigarette Smoking-Related Carcinoma

Treatments: Other: Health Promotion and Education; Behavioral: Smartphone App-delivered Smoking Cessation Intervention; Other: Biospecimen Collection; Other: Questionnaire Administration

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06386432

U54CA132381 (U.S. NIH Grant/Contract)

FHIRB0020404 (Other Identifier)

RG1124189 (Other Identifier)

NCI-2024-02453 (Registry Identifier)

Details and patient eligibility

About

This clinical trial assesses the acceptability and efficacy of Empowered, Queer, Quitting, and Living--New Mexico (EQQUAL-NM), a smoking cessation intervention for sexual and gender minority young adults in New Mexico. Smoking prevalence among sexual and gender minority (SGM) adults in New Mexico is more than twice as high as non-SGM adults. Helping young adult tobacco users to quit is critical, yet there have been few efforts to develop tailored treatments specifically for this population. EQQUAL-NM is a digital smoking cessation intervention designed specifically for SGM young adult smokers in New Mexico and may help them quit smoking.

Full description

OUTLINE:

Participants are randomized to 1 of 2 groups.

GROUP I: Participants receive access to a self-guided, smartphone app-delivered quit smoking program, called EQQUAL-NM (Program A) that helps explore personal values and teaches participants about smoking triggers and skills to help them manage cravings and accept thoughts and feelings related to smoking. Participants receive text message reminders and prompts on study. Some participants also undergo collection of a saliva sample during follow-up.

GROUP II: Participants receive access to a self-guided, smartphone app-delivered quit smoking program, called EQQUAL-NM (Program B) that is based on current clinical practice guidelines for tobacco cessation to help them quit smoking. This program helps with quit advice, tracking progress on quitting smoking, and managing cravings. Participants receive text message reminders and prompts on study. Some participants also undergo collection of a saliva sample during follow-up.

After completion of study intervention, patients are followed up at 3 months.

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Self-identify being between 18 and 30 years of age
• Self-identify as a sexual and/or gender minority (i.e., a sexual orientation other than straight and/or gender that doesn't match sex assigned at birth)
• Currently reside in New Mexico, with a New Mexico mailing address, and anticipate remaining in New Mexico for the duration of the study (3 months)
• Self-report smoking at least 1 cigarette per week in the 30 days prior to screening
• Own an Android phone or iPhone
• Have at least weekly internet access for the next three months
• Willing and able to stream audio and video for this study
• Current use of a personal email account
• Current use of text messaging
• Interested in participating in the study for themselves (versus [vs] someone else)
• Self-report that they have not participated in one of Fred Hutch's/NMSU's prior smoking cessation studies
• Understand and agree to the conditions of compensation
• Currently not incarcerated
• Participants must be willing to use the assigned intervention program, complete the study assessments, and agree to the online consent form in English

Exclusion criteria

• Current use of other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (but initiating these treatments during the study is allowed)
• Member of the same household as another research participant
• Previous use of the National Cancer Institute (NCI) QuitGuide app
• Google voice number as sole phone number
• Does not pass study fraud prevention protocol

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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0 participants in 2 patient groups

Arm I (EQQUAL-NM, Program A)

Experimental group

Description:

Participants receive self-guided smartphone app-delivered EQQUAL-NM (Program A) intervention on study. Participants also receive motivational messages, reminders and smoking cessation information via text messages. Some participants also complete at-home saliva sample collection during follow-up.

Treatment:

Other: Questionnaire Administration

Other: Biospecimen Collection

Behavioral: Smartphone App-delivered Smoking Cessation Intervention

Other: Health Promotion and Education

Other: Health Promotion and Education

Behavioral: Smartphone App-delivered Smoking Cessation Intervention

Arm II (EQQUAL-NM, Program B)

Active Comparator group

Description:

Participants receive self-guided smartphone app-delivered EQQUAL-NM (Program B) intervention on study. Participants also receive motivational messages, reminders and smoking cessation information via text messages. Some participants also complete at-home saliva sample collection during follow-up.

Treatment:

Other: Questionnaire Administration

Other: Biospecimen Collection

Behavioral: Smartphone App-delivered Smoking Cessation Intervention

Other: Health Promotion and Education

Other: Health Promotion and Education

Behavioral: Smartphone App-delivered Smoking Cessation Intervention