Erector Spinae Block for Thoracoscopic Surgery

St. Antonius Hospital

Status: Completed

Conditions: Postoperative Pain; Thoracic Neoplasms

Treatments: Procedure: Erector Spinae Plane Block (for postoperative pain relief)

Study type: Interventional

Funder types: Other

Identifiers

NCT04751552

L20.047

Details and patient eligibility

About

This randomized clinical trial compares the effects of the erector spinae plane block with levobupivacaine and 0,9% saline on postoperative pain intensity, and opioid consumptions following thoracoscopic pulmonary surgery.

Full description

Sixty patients planned for thoracoscopic pulmonary surgery are randomly assigned to an erector spinae plane block (ESPB) with levobupivacaine (intervention group) or 0,9% saline (control group). ESPB is performed under general anaesthesia before surgery.

Postoperative pain medication incudes acetominophen, NSAIDs en parenteral morphine (patient controlled analgesia).

Following surgery pain intensity (numeric rating scale) is registered at the recovery ward one hour after surgery. Furthermore, pain intensity is registered 2,4,8, 12 hours after the operation. On the first postoperative day, pain intensity is registered at 8.00 o'cock AM and 8.00 o'clock PM. Opioid consumption is registered as a second parameter of postoperative pain.

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for thoracoscopic pulmonary sleeve resection or lobectomy

• Age 18 years or older

  • American Society of Anesthesiologists (ASA) health status class I-III
  • Informed consent

Exclusion criteria

• Contraindication for regional analgesia (e.g. coagulopathy, infection at injection site)
• Contraindication for NSAIDs
• Chronic opioid use
• Pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Levobupivacaine group

Active Comparator group

Description:

Patients receive an ESPB with the local anaesthetic levobupivacaine

Treatment:

Procedure: Erector Spinae Plane Block (for postoperative pain relief)

Placebo group

Placebo Comparator group

Description:

Patients receive an ESPB with 0,9% saline

Treatment:

Procedure: Erector Spinae Plane Block (for postoperative pain relief)