Erector Spinae Plane Block Versus Modified Thoracolumbar Interfascial Plane Block

Zagazig University

Status: Invitation-only

Conditions: Achievement of High-quality Analgesia, Rapid Recovery With Rehabilitation in Lumber Spine Discectomy

Treatments: Drug: Regional Anesthetic Injection

Study type: Interventional

Funder types: Other

Identifiers

NCT06910696

ZU-IRB#1074/25-Feb-2025

Details and patient eligibility

About

the purpose of this study is to compare of better postoperative analgesia following lumber spine discectomy

Enrollment: 144 estimated patients

Sex: All

Ages: 21 to 64 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Written informed consent from the patient.
• Physical status: ASA 1& II.
• BMI = (25-30 kg/m2).
• Type of operation: elective Lumbar discectomy .

Exclusion criteria

• Altered mental state.
• Patients with known history of allergy to study drugs.
• Advanced hepatic, renal, cardiovascular, and respiratory diseases.
• Patients with chronic pain.
• Patients receiving anticoagulants.
• Contraindications of regional anesthesia, e.g., allergy to local anesthetics, coagulopathy, or septic focus at site of injection.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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144 participants in 3 patient groups

• Control Group

No Intervention group

Description:

Patients will receive standard analgesia (paracetamol 15mg/kg plus fentanyl 1ug/kg) iv.

(mTLIP )Group

Active Comparator group

Description:

Patients will receive 20 mL of 0.25% bupivacaine on each side through Modified thoracolumbar interfascial block

Treatment:

Drug: Regional Anesthetic Injection

Drug: Regional Anesthetic Injection

(ESPB) Group

Active Comparator group

Description:

Patients will receive 20 mL of 0.25% bupivacaine on each side through Erector spinae block

Treatment:

Drug: Regional Anesthetic Injection

Drug: Regional Anesthetic Injection