Erector Spinae Plane Block Versus Perioperative Intravenous Lidocaine for Thoracotomy

Ataturk University

Status: Completed

Conditions: Thoracic Diseases

Treatments: Drug: Saline Solution intravenously; Drug: Bupivacaine Hcl 0.25% Inj; Drug: Lidocaine; Drug: Saline Solution for Block

Study type: Interventional

Funder types: Other

Identifiers

NCT04221880

ESP vs Lidocaine

Details and patient eligibility

About

Thoracotomy surgery is the most painful of all surgical procedures. Inadequate postoperative pain control in these patients may cause serious morbidity related to pulmonary, cardiovascular and emotional systems. Erector Spinae Plane Block (ESPB) was first described in 2016 and, it is frequently used for postoperative analgesia in thoracic surgery. Intravenous lidocaine exhibit analgesic activity through both the peripheral and central nervous system. Intravenous lidocaine has been shown to reduce postoperative pain intensity and accelerate postoperative recovery in many surgeries.

The investigators aimed to compare the effect of lidocaine infusion and erector spinae plane block on postoperative opioid consumption and pain scores.

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologist's physiologic state I-III patients undergoing thoracotomy surgery

Exclusion criteria

• chronic pain, bleeding disorders, renal or hepatic insufficiency, non cooperative patient,
• Patients with allergies to one of the drugs used in the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 3 patient groups

Group ESPB

Active Comparator group

Description:

Ultrasound-guided erector spinae plane block with 20 ml %0.25 bupivacaine and Saline iv. bolus and infusion (same volume as Group Lidocaine)

Treatment:

Drug: Bupivacaine Hcl 0.25% Inj

Drug: Saline Solution intravenously

Group Lidocaine

Active Comparator group

Description:

1.5 mg / kg lidocaine iv. bolus and, 1.5mg / kg / h lidocaine iv. infusion and, Ultrasound-guided erector spinae plane block with 20 ml saline

Treatment:

Drug: Saline Solution for Block

Drug: Lidocaine

Group Control

Sham Comparator group

Description:

Ultrasound-guided erector spinae plane block with 20 ml saline and, Saline iv. bolus and infusion (same volume as Group Lidocaine)

Treatment:

Drug: Saline Solution for Block

Drug: Saline Solution intravenously