Erector Spinae Plane Block Vs. IPACK Block with Adductor Canal Block for Total Knee Arthroplasty

Poznan University of Medical Sciences (PUMS)

Status and phase: Completed; Phase 4

Conditions: Knee Arthritis; Knee Pain Chronic; Knee Osteoarthritis

Treatments: Drug: Ropivacaine 0.2% Injectable Solution iPACK+ACB; Drug: Control Test - spinal anesthesia; Drug: Ropivacaine 0.2% Injectable Solution ESPB

Study type: Interventional

Funder types: Other

Identifiers

NCT06233630

4/2024

Details and patient eligibility

About

Effect of Erector Spinae Plane Block and iPACK block with Adductor Canal Block on pain management, and NLR and PLR following knee arthroplasty

Full description

Knee arthroplasty is one of the most common orthopedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prosthesis. Regional anesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.

In recent years, the influence of regional anesthesiology on reducing the inflammatory response after surgical procedures has been emphasized. However, very few studies have evaluated the effect of various methods of anesthesia on the NLR.

Enrollment: 90 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with ASA classification I-III,
• Aged 20-100 years,
• scheduled for knee arthroplasty under spinal anaesthesia

Exclusion criteria

• Patients who have a history of bleeding diathesis,
• Take anticoagulant therapy,
• have a History of chronic pain before surgery,
• have Multiple trauma,
• cannot assess their pain (dementia),
• have been operated on under general anaesthesia,
• have an infection in the area
• do not accept the procedure

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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90 participants in 3 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Only spinal anaesthesia - No peripheral nerve block

Treatment:

Drug: Control Test - spinal anesthesia

Erector Spinae Plane Block

Active Comparator group

Description:

spinal anaesthesia and unilateral ultrasound guided erector spinae plane block - 20ml 0.2% ropivacaine

Treatment:

Drug: Ropivacaine 0.2% Injectable Solution ESPB

Infiltration Popliteal Artery and Capsule of the Knee and Adductor Canal Block

Active Comparator group

Description:

spinal anaesthesia and ultrasound guided Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee (iPACK) block - 20ml 0.2% ropivacaine + ultrasound guided Adductor Canal Block - 10ml 0.2% ropivacaine

Treatment:

Drug: Ropivacaine 0.2% Injectable Solution iPACK+ACB