Erector Spinae Plane Block vs. iPACK Block With Adductor Canal Block for Total Knee Arthroplasty

P

Poznan University of Medical Sciences (PUMS)

Status and phase

Not yet enrolling
Phase 4

Conditions

Knee Arthritis
Knee Pain Chronic
Knee Osteoarthritis

Treatments

Drug: Ropivacaine 0.2% Injectable Solution iPACK+ACB
Drug: Control Test - spinal anesthesia
Drug: Ropivacaine 0.2% Injectable Solution ESPB

Study type

Interventional

Funder types

Other

Identifiers

NCT06233630
4/2024

Details and patient eligibility

About

Effect of Erector Spinae Plane Block and iPACK block with Adductor Canal Block on pain management, and NLR and PLR following knee arthroplasty

Full description

Knee arthroplasty is one of the most common orthopedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prosthesis. Regional anesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects. In recent years, the influence of regional anesthesiology on reducing the inflammatory response after surgical procedures has been emphasized. However, very few studies have evaluated the effect of various methods of anesthesia on the NLR.

Enrollment

30 estimated patients

Sex

All

Ages

18 to 100 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients with ASA classification I-III,
  • Aged 20-100 years,
  • scheduled for knee arthroplasty under spinal anaesthesia

Exclusion criteria

  • Patients who have a history of bleeding diathesis,
  • Take anticoagulant therapy,
  • have a History of chronic pain before surgery,
  • have Multiple trauma,
  • cannot assess their pain (dementia),
  • have been operated on under general anaesthesia,
  • have an infection in the area
  • do not accept the procedure

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

30 participants in 3 patient groups, including a placebo group

Placebo
Placebo Comparator group
Description:
Only spinal anaesthesia - No peripheral nerve block
Treatment:
Drug: Control Test - spinal anesthesia
Erector Spinae Plane Block
Active Comparator group
Description:
spinal anaesthesia and unilateral ultrasound guided erector spinae plane block - 20ml 0.2% ropivacaine
Treatment:
Drug: Ropivacaine 0.2% Injectable Solution ESPB
Infiltration Popliteal Artery and Capsule of the Knee and Adductor Canal Block
Active Comparator group
Description:
spinal anaesthesia and ultrasound guided Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee (iPACK) block - 20ml 0.2% ropivacaine + ultrasound guided Adductor Canal Block - 10ml 0.2% ropivacaine
Treatment:
Drug: Ropivacaine 0.2% Injectable Solution iPACK+ACB

Trial contacts and locations

1

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Central trial contact

Malgorzata Domagalska, Ph.D.; Katarzyna Wieczorowska-Tobis, Ph.D.

Data sourced from clinicaltrials.gov

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