ERILs Und SNILs Unter SOC

Medical University of Vienna

Status: Withdrawn

Conditions: Stroke, Acute

Treatments: Diagnostic Test: diffusion-weighted magnetic resonance imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT05786170

ERILs und SNILs unter SOC

Details and patient eligibility

About

1. How many ERILs occur in caucasian patients with LAA stroke during 7 days on standard treatment?
2. How many SNILs occur between 7 and 30 days after acute ischemic event on standard treatment?
3. How many of during acute event diagnosed lesions (ERILs) are (still) detectable after 30 days?
4. Are there relevant risk faktors for the occurence of ERILs and SNILs (eg Diabetes or Biomarkers)?

Full description

In this trial, patients will be observed if they develop early recurrent ischemic lesions (= ERILs) or silent neurologic ischemic lesions (= SNILs) after acute stroke or transitoric ischemic attack (TIA) based on atherothrombosis (LAA-stroke) on standard therapy during 30 days (day 7 and day 30 after acute event) via DW-MRI (diffusion-weighted magnetic resonance imaging).

We want to investigate if diffusion-weighted imaging of silent brain infarcts occuring during standard therapy is a suitable surrogate outcome measure for interventional studies

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• LAA stroke or TIA
• ERILs or SNILs detected in initialDW-MRI
• signed informed consent

Exclusion criteria

• planned surgical intervention
• iv Thrombolysis
• atrial fibrillation
• contra indications against DW-MRI

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

magnetic resonance imaging

Experimental group

Description:

DW-MRI after ischemic stroke

Treatment:

Diagnostic Test: diffusion-weighted magnetic resonance imaging