Erythema Migrans in Elderly

University Medical Centre Ljubljana

Status: Completed

Conditions: Erythema Migrans; Elderly Infection; Lyme Disease

Treatments: Other: no intervention; Drug: Antibiotics

Study type: Observational

Funder types: Other

Identifiers

NCT03371563

EM-elderly

Details and patient eligibility

About

The investigators will focus on elderly patients with early Lyme borreliosis with the aim of assessing clinical course, serological response and treatment outcome of the disease as compared to younger adults. Furthermore, the investigators will compare the prevalence of nonspecific symptoms among patients and among age-matched controls without a history of Lyme borreliosis.

Enrollment: 1,220 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• erythema migrans

Exclusion criteria

• pregnancy or lactation
• immunocompromised
• taking antibiotic with antiborrelial activity within 10 days
• received <10 days of antibiotic therapy for erythema migrans
• had an intercurrent episode of Lyme borreliosis during follow-up

Trial design

1,220 participants in 4 patient groups

elderly patients

Treatment:

Drug: Antibiotics

middle-aged patients

Treatment:

Drug: Antibiotics

controls

Treatment:

Other: no intervention

young patients

Treatment:

Drug: Antibiotics