Erythrocyte Complement Receptor 1 and Alzheimer Disease

CHU de Reims

Status: Completed

Conditions: Alzheimer Disease

Treatments: Other: CR1 impact

Study type: Interventional

Funder types: Other

Identifiers

NCT01565434

PA11014

Details and patient eligibility

About

Main objective: investigate whether a functional polymorphism of CR1 (length, number of binding sites in C4b C3b, erythrocyte density, rate of soluble CR1 ...) so determined genetic or acquired, is a susceptibility factor for the disease Alzheimer's.

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• caucasians people with a Alzheimer dementia defined on DSMIV criteria for patients and without Alzheimer disease for control subjects

Exclusion criteria

• diseases modifying CR1 physiology