"Escape" Phenomenon of the Antihypertensive Therapy Efficacy (ESCAPE)

Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADE

Status: Active, not recruiting

Conditions: Arterial Hypertension

Treatments: Device: VaSera-VS; Device: Sphygmocor; Device: Ambulatory blood pressure measurement device; Device: Somnocheck

Study type: Observational

Funder types: Other

Identifiers

NCT05436730

115061870017

Details and patient eligibility

About

A little attention is paid to the AHT efficacy escaping problem, which can be explained by the AHT correction simplicity and rapid achievement of the target BP level. Nevertheless, modern statistic data on the effective AH treatment described above let us assume that AHT correction is either totally absent or is untimely in case of the "escape" phenomenon development. This could be one of the main reasons for the high prevalence of ineffective AH treatment. The aim of this study is to determine AHT efficacy "escape" phenomenon timeline and its predictors in hypertensive patients.

Enrollment: 165 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Arterial hypertension (AH) grade 1-3, stage I-II
• High compliance during the follow-up period (≥ 85%)
• Initially achieved target office BP levels while taking 2-3-component AHT

Exclusion criteria

• Secondary AH
• Resistant AH,
• AH III stage,
• PAP- therapy,
• type 2 diabetes mellitus,
• pregnancy
• history of low adherence to treatment

Trial design

165 participants in 1 patient group

"Escape" Phenomenon of the Antihypertensive Therapy Efficacy

Description:

Men and women aged 18-90 years with arterial hypertension grade 1-3, stage I-II and initially achieved target BP levels while taking 2-3-component AHT.

Treatment:

Device: Ambulatory blood pressure measurement device

Device: Somnocheck

Device: Sphygmocor

Device: VaSera-VS