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Esophageal Manometry in Mechanically Ventilated Patients

S

Sahlgrenska University Hospital

Status

Completed

Conditions

Acute Respiratory Failure

Study type

Observational

Funder types

Other

Identifiers

NCT02901158
LUA-74203

Details and patient eligibility

About

Esophageal pressure measurements are used in to determine chest wall elastance and calculate lung elastance and transpulmonary pressure in mechanically ventilated patients. A dedicated esophageal balloon catheter is then placed in the esophagus to measure tidal variations in esophageal pressure.

In this study high resolution solid-state manometry technique was used to provide detailed and continuous measurements of esophageal pressures in the different parts of the esophagus. Measurements were performed during ongoing mechanical ventilation at different levels of endexpiratory pressure.

Full description

Esophageal pressure measurements are used in to determine chest wall elastance and calculate lung elastance and transpulmonary pressure in mechanically ventilated patients. A dedicated esophageal balloon catheter is then placed in the esophagus to measure tidal variations in esophageal pressure.

In this study high resolution solid-state manometry technique was instead used to provide detailed and continuous measurements of esophageal pressures in the different parts of the esophagus. The manometry catheter has 36 circumferential sensors at 1 cm intervals. Each sensor has 12 pressure-sensitive segments that add to the signal at that location. Measurements were performed during ongoing mechanical ventilation at different levels of endexpiratory pressure. Possible differences in tidal variations in esophageal pressure in different parts of the esophagus were assessed.

Enrollment

20 patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients in the critical care unit receiving mechanical ventilation or Patients anesthetized and undergoing surgery

Exclusion criteria

  • Patients with a contraindication to insert a catheter in the esophagus for instance due to an operation.

Trial design

20 participants in 2 patient groups

Critical care patients
Description:
Mechanically ventilated patients in the critical care unit
OR-patients
Description:
Mechanically ventilated patients in the operating room

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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