Esophageal Motility Disease Screening in Patient With Suspicion or Diagnosis of IBD (EMSIBD)

University Hospital Erlangen

Status: Unknown

Conditions: Inflammatory Bowel Disease

Treatments: Device: Manometry

Study type: Interventional

Funder types: Other

Identifiers

NCT02478944

Gastrolabor-IBD UKE

Details and patient eligibility

About

Aims: Prospective evaluation of patients with a suspicion or diagnosis of Inflammatory bowel disease (IBD) to evaluate osophageal motility before and during therapy

Material and methods: The investigators prospectively perform manometry in patients with or with symptoms consistent with IBD. The investigators evaluate esophageal motility with high resolution manometry before, during and after IBD therapy. Clinical data are also collected to find possible correlations. The study do not modify the planned IBD therapy, but observe motility findings.

Full description

Oesophageal motility is measured with the high resolution manometry in order to detect pathologic peristaltic amplitude values among patient before and after therapy (mesalazine, steroids, biologicals) compared to the standard values detected among the normal population. Diagnosic intervention like oesophagoduodenoscopy, colonoscopy and stenosis ballon dilation are allowed as are part of the IBD therapy and follow up.

No other interventions are administered to participants during this study.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Inflammatory bowel disease
• Suspicion of inflammatory bowel disease

Exclusion criteria

• Pregnancy

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

Inflammatory bowel disease

Experimental group

Description:

Patients with Crohn's disease and ulcerative colitis undergoing manometry

Treatment:

Device: Manometry