Esophagectomy in Patients With Liver Cirrhosis

Universitätsklinikum Hamburg-Eppendorf

Status: Completed

Conditions: Esophageal Cancer; Liver Cirrhosis

Treatments: Procedure: surgery

Study type: Observational

Funder types: Other

Identifiers

NCT04809870

UKE Hamburg

Details and patient eligibility

About

Retrospective and confounder adjusted comparison of perioperative and longterm outcomes of patients requiring an esophagectomy for esophageal cancer with and without concomitant liver cirrhosis.

Enrollment: 170 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age ≥ 18 years
• primary esophageal cancer with indication for curative treatment
• follow up period ≥ 5 years
• LC cohort: pre- or intraoperative histological proof of liver cirrhosis

Exclusion criteria

• recurrent esophageal cancer
• missing indication for curative treatment of esophageal cancer
• esophagectomy for benign esophageal lesions

Trial design

170 participants in 2 patient groups

LC (liver cirrhotic patients)

Description:

Patients with concomitant liver cirrhosis

Treatment:

Procedure: surgery

Non-LC (non liver cirrhotic patients)

Description:

Patients without concomitant liver cirrhosis

Treatment:

Procedure: surgery