ESPB vs TPVB for Postoperative Analgesia After the Nuss Procedure

Sichuan University

Status: Completed

Conditions: Nerve Block; Analgesia; Pectus Excavatum

Treatments: Procedure: ESPB group; Procedure: TPVB group

Study type: Interventional

Funder types: Other

Identifiers

NCT05034601

2021-866

Details and patient eligibility

About

This is a prospective randomized double-blind non-inferiority trial designed to test the hypothesis that erector spinae plane block (ESPB) is non-inferior to thoracic paravertebral block (TPVB) in postoperative pain control after pectus excavatum repair.

Enrollment: 68 patients

Sex: All

Ages: 4 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 4 to 18 years Scheduled for elective Nuss surgery Written informed consent is obtained from parents of each patient.

Exclusion criteria

• Coagulation dysfunction. American Society of Anesthesiologists Physical Status 4 or 5. Allergy to study medication. Local infection at the site of injection or systemic infection. Inability to understand Chinese.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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68 participants in 2 patient groups

ESPB group

Experimental group

Description:

0.25% ropivacaine 0.5 ml/kg is injected at the fascial plane deep to the erector spinae muscle

Treatment:

Procedure: ESPB group

TPVB group

Active Comparator group

Description:

0.25% ropivacaine 0.5 ml/kg is injected into the thoracic paravertebral space (T5) using TPVB approach.

Treatment:

Procedure: TPVB group