Establish a Vegetable Signature Database From Human Metabolomics Responses

National Health Research Institutes, Taiwan

Status

Unknown

Conditions

Human Metabolomic Responses to Plant Foods

Blood Pressure

Treatments

Other: Low phytochemical diet(LPD), high phytochemical diet(HPD)

Study type

Interventional

Funder types

Other

Identifiers

NCT01600911

EC0991003

Details and patient eligibility

About

Vegetable is well known to prevent chronic disease,however, the mechanism of its nutrients and non-nutrients still remains to be discovered.We design a feeding study which provides plant foods to subjects one by another and monitoring metabolomic changes up to 7 hours.The goal of this study is to establish a protocol for documenting metabolomics response to plant foods and try to characterize plant foods in terms of their anti-hypertension potentials with metabolomic profiling information.

Enrollment

50 estimated patients

Sex

All

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age :18-60 years
Body Mass Index :18.5-30(kg/m2)
Non-smoking,alcohol abusing,and other bad hobbies

Exclusion criteria

With regular drug intake e.g. anti-hypertensive or antidiabetes drug or history of immune, hepatic and metabolic disease or other unsuitable disorders e.g. cancer.
unwilling to stop regular food supplement e.g. vitamins, herb
cannot cooperate with designed diet
History of urinary tract infection or antibiotic use within the previous 3 month