Establish the First International Database on Semi-quantitative Values Obtained in Scintigraphy With Datscan® in Cadmium-Zinc-Telluride Camera (DaTBase)

Central Hospital, Nancy, France

Status: Not yet enrolling

Conditions: Neurodegenerative Diseases

Treatments: Other: datscan scintigraphy

Study type: Observational

Funder types: Other

Identifiers

NCT06828705

2024PI206

Details and patient eligibility

About

Datscan scintigraphy is a nuclear medicine examination allowing the diagnosis of neurodegenerative pathologies linked to damage to dopaminergic pathways, such as Parkinson's disease (essential for the differential diagnosis of essential tremor).

Full description

Datscan scintigraphy is a nuclear medicine examination allowing the diagnosis of neurodegenerative pathologies linked to damage to dopaminergic pathways, such as Parkinson's disease (essential for the differential diagnosis of essential tremor).

There are several types of cameras allowing its performance:

• Conventional Anger cameras and,
• CZT (Cadmium-Zinc-Telluride) semiconductor cameras. At the Nancy University Hospital, the nuclear medicine department has a wide-field Cadmium-Zinc-Telluride camera: VERITON-CT (Spectrum Dynamics). The interpretation of this examination is purely visual.

The objectives are therefore to:

• Create the first international database of semi-quantitative values in 3D scintigraphy with Datscan performed with a VERITON-CT camera.
• Compare this database with another database from a conventional Anger camera (Lyon Nuclear Medicine Department) to show its superiority.

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients who have undergone a Datscan scintigraphy on the VERITON camera in the nuclear medicine department of the Nancy University Hospital and who have an established clinical diagnosis, -Absence of neurodegenerative pathology or Parkinson's disease or Lewy body disease.
• The clinical diagnosis can only be established after two years of clinical follow-up.

Exclusion criteria

• Excluded from this research will be the patients opposed to the use of their data, minors, atypical Parkinsonian syndromes,
• patients who died before two years of clinical follow-up,
• patients who had their Datscan examination carried out on a camera other than the VERITON and - patients lost to follow-up.