Establishing First Trimester Markers for the Identification of High Risk Twin

Shamir Medical Center (Assaf-Harofeh)

Status: Unknown

Conditions: Pre-Eclampsia; Small for Gestational Age (Disorder)

Study type: Observational

Funder types: Other

Identifiers

NCT02031393

217/13

Details and patient eligibility

About

The purpose of this study is to determine whether we can establish different markers suc as mean arterial pressure , flow in the uterine arteries, biochemical markers in maternal blood and more un the first trimester, in order to screen for twin pregnancies that are more likely to develop adverse pregnancy outcome: early delivery, pre eclampsia or small fetuses.

Enrollment: 300 estimated patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• pregnant women from 11 -14 weeks of gestation

Exclusion criteria

• nuchal thickness above 3 mm,
• Chronic hypertension,
• thrombophilia,
• Diabetes

Trial design

300 participants in 2 patient groups

singelton pregnancy

Description:

will be followed 11-14 weeks and 19-28 weeks of gestation and after birth

twin pregnancy

Description:

will be followed 11-14 weeks and 19-28 weeks of gestation and after birth