Establishing the Central and Peripheral Fatigue Indexes and VR Based Anti-fatigue Training Paradigm for Individuals With Parkinson Disease

Chang Gung University

Status: Completed

Conditions: Parkinson's Disease (PD)

Treatments: Procedure: Virtual Reality anti-fatigue ergo cycling training (Self-made)

Study type: Interventional

Funder types: Other

Identifiers

NCT02017938

101-5141B

Details and patient eligibility

About

Fatigue is one of the most common symptoms in individuals with Parkinson's Disease (PD). Past researches indicated that more than half of the individuals with PD demonstrated fatigue symptom. The severity of fatigue was also correlated to the quality of life in individuals with PD. Finding the contributions of the central and the peripheral factors to fatigue, building reliable fatigue indexes, and developing an effective training program for individuals with PD are very important.

The purpose of this project is to develop non-invasive method to monitor central and peripheral fatigue, to establish Virtual Reality(VR) anti-fatigue ergo cycling training paradigm, and to evaluate the long term training effect in individuals with PD.

Enrollment: 31 patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Parkinson disease
• Hoehn and Yahr ≦3

Exclusion criteria

• Musculoskeletal injuries
• Osteoporosis
• Diabetes
• Any peripheral or central nervous system injury or disease patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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31 participants in 5 patient groups

Stage 1: Health group

No Intervention group

Description:

To establish non-invasive fatigue monitoring method via testing healthy individuals.

Stage 2: PD group

Experimental group

Description:

To find the optimal feedback variables for anti-fatigue training on individuals with PD.

Treatment:

Procedure: Virtual Reality anti-fatigue ergo cycling training (Self-made)

Stage 2: Health group

Experimental group

Description:

Stage 2 controlled group

Treatment:

Procedure: Virtual Reality anti-fatigue ergo cycling training (Self-made)

Stage 3: PD group

Experimental group

Description:

To evaluate the effect of four weeks of VR anti-fatigue ergo cycling training on various fatigue components and functional abilities in individuals with PD.

Treatment:

Procedure: Virtual Reality anti-fatigue ergo cycling training (Self-made)

Stage 3: PD controlled group

No Intervention group

Description:

Stage 3 controlled group