Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland (STARR)

University of Aberdeen

Status: Enrolling

Conditions: Myocardial Infarction; Takotsubo Cardiomyopathy

Study type: Observational

Funder types: Other

Identifiers

NCT03299569

16/LO/1059

Details and patient eligibility

About

Acute stress-induced (Takotsubo cardiomyopathy) presents like a heart attack and is triggered by intense emotional or physical stress. Although coronary arteries are unobstructed, it has been suggested that the risk of death is similar to a myocardial infarction. The purpose of the STARR study is to identify all cases of Takotsubo in Scotland since 2010 and assess its epidemiology and outcomes.

Full description

Public Health Scotland will identify all patients centrally coded under codes I42.8 (Other cardiomyopathies), I42.9 (Cardiomyopathy, unspecified) and I51.8 (Other ill-defined heart diseases), using the Community Health Index (CHI) numbers from January 2010. All identified CHI numbers will be thereafter cross-checked with their clinical data at participating health boards to confirm a diagnosis of takotsubo cardiomyopathy and a registry of all confirmed Takotsubo cases will be established.

Clinical data will be collected for all Takotsubo patients retrospectively and prospectively. This will be compared to two contemporaneous gender and age matched control populations:

1. a cohort of randomly selected individuals from the Scottish general population supplied by Public Health Scotland
2. patients with myocardial infarction (extracted through collaboration with, the High-STEACS investigators, NCT01852123).

Electronic data linkage will be performed by Public Health Scotland to assess outcomes, prescribing and scores of prediction.

Enrollment: 800 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients diagnosed with Takotsubo cardiomyopathy

Exclusion criteria

• NA

Trial design

800 participants in 2 patient groups

Takotsubo cardiomyopathy

Description:

All patients diagnosed with Takotsubo cardiomyopathy in Scotland since 2010.

Myocardial Infarction

Description:

An equal number of myocardial infarction patients in NHS Grampian since 2010.