Establishment of a Method for Extraction and Quantification of Gingival Tissue Nicotine y

University of Liege

Status: Enrolling

Conditions: Smoking, Cigarette

Treatments: Diagnostic Test: biopsie

Study type: Observational

Funder types: Other

Identifiers

NCT05736250

2021:250

Details and patient eligibility

About

establishment of a method for extraction and quantification of gingival tissue nicotine in relation to conventional tobacco biomarkers: a pilot study

Full description

The study aim to establish a method for extraction and quantification of gingival tissue nicotine. Additionnaly, the relationship between the nicotine tissue intoxication with others smoking indicators will be evaluated as mentionned in the following PICO question:

• P: Smoker patients
• I: Biopsie of gingival tissue
• C: Non-smoker patient
• O: nicotine dependence test (FTND), salivary cotinine, fibroblast nicotine, number of cigarette consumed per day (NCC) and the pack-year (PY)

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• non smokers
• smokers

Exclusion criteria

• not able to have biopsie

Trial design

20 participants in 1 patient group

TEST group

Description:

smoker patients

Treatment:

Diagnostic Test: biopsie