Establishment of a Tumor Bank for Blood Samples

Medical University of Vienna

Status: Enrolling

Conditions: Lung Neoplasms; Ovarian Neoplasms; Endocrine Gland Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Neoplasms of the Female Genitalia

Treatments: Other: Blood collection

Study type: Observational

Funder types: Other

Identifiers

NCT01763125

EK 366/2003

Details and patient eligibility

About

Establishment of a tumor bank, consisting of blood samples of tumor patients and healthy people as controls. The blood samples will be collected systematically together with the corresponding clinical data. The biological samples, the clinical date together with prospective experimental date constitute the entity of the tumor bank.

Full description

Recent progress in diagnosis and therapy of cancer diseases can be ascribed mainly to translational research. The relevance of "translational oncology" will only increase in the future -"From bench to bedside" - the swift implementation of new science research results in clinical studies in order to expedite progress in clinical cancer therapy for the benefit of the patient.

Its almost a matter of course in the medical science today to collect biological samples together with clinical information thereby creating the foundation for future excellent fundamental research.

The aim of this tumor bank is to consist of biological samples (together with a tissue bank - see EK 260/2003) and isolates of tumor patients and healthy people as controls. The biological samples, the clinical date together with prospective experimental date constitute the entity of the tumor bank. The content of the tumor bank can provide essential material for current and future research (e.g. analyses of prognostic or predictive tumor markers; genetically analysis (polymorphism, mutation, hypermethylation; verification and characterisation of disseminated tumor cells).

Enrollment: 10,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male/Female
• Age 18 to 90 years max.
• Just one current known malignant disease or
• Just one current inflammatory disease

Exclusion criteria

• Inflammatory disease and malignant disease
• multiple malignancies
• multiple diseases
• underage

Trial design

10,000 participants in 3 patient groups

Malignant tumors

Description:

Patients who have one of the Neoplasms stated above under "conditions". Blood samples will be taken.

Treatment:

Other: Blood collection

Benign controls

Description:

Patients with a benign tumor or an inflammatory disease - to be matched by age and affected organ with a patient with a malignant disease. Blood samples will be taken.

Treatment:

Other: Blood collection

Healthy controls

Description:

People/patients who have no known disease at time of blood sampling or are admitted to the hospital for minor interventions and have no inflammatory disease. Blood samples will be taken.

Treatment:

Other: Blood collection