Establishment of a Tumor Bank for Tissue Samples

Medical University of Vienna

Status: Enrolling

Conditions: Lung Neoplasms; Ovarian Neoplasms; Endocrine Gland Neoplasms; Breast Neoplasms; Neoplasms of the Female Genitalia; Colorectal Neoplasms

Treatments: Other: Collecting stool samples; Other: Sampling of ascites and pleural effusion; Other: Collecting sputum; Other: Collecting urine samples; Other: Tumor tissue collection; Other: Lavage/Irrigation; Other: Collecting saliva sample

Study type: Observational

Funder types: Other

Identifiers

NCT01789229

EK 260/2003

Details and patient eligibility

About

Establishment of a tumor bank, consisting of tissue samples of tumor patients (benign and malign tumors) and healthy people as controls. The tissue samples will be collected systematically together with the corresponding clinical data. The biological samples, the clinical date together with prospective experimental date constitute the entity of the tissue tumor bank.

This tumor bank for tissue samples, together with our tumorbank for blood samples (NCT01763125) combined constitute the entity "Tumorbank".

Full description

Recent progress in diagnosis and therapy of cancer diseases can be ascribed mainly to translational research. The relevance of "translational oncology" will only increase in the future -"From bench to bedside" - the swift implementation of new science research results in clinical studies in order to expedite progress in clinical cancer therapy for the benefit of the patient.

Its almost a matter of course in the medical science today to collect biological samples together with clinical information thereby creating the foundation for future excellent fundamental research.

The aim of this tumor bank is to consist of biological samples (together with a blood bank - see NCT01763125) and isolates of tumor patients and healthy people as controls. The biological samples, the clinical date together with prospective experimental date constitute the entity of the tumor bank. The content of the tumor bank can provide essential material for current and future research (e.g. analyses of prognostic or predictive tumor markers; genetically analysis (polymorphism, mutation, hypermethylation; verification and characterisation of disseminated tumor cells).

Enrollment: 10,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male/Female
• Age 18 to 90 years max.
• Just one current known malignant disease or just one current inflammatory disease

Exclusion criteria

• Inflammatory disease and malignant disease
• multiple malignancies
• multiple diseases
• underage

Trial design

10,000 participants in 3 patient groups

Malignant tumors

Description:

Patients who have one of the Neoplasms stated above under "conditions".

Treatment:

Other: Collecting saliva sample

Other: Lavage/Irrigation

Other: Tumor tissue collection

Other: Collecting urine samples

Other: Collecting sputum

Other: Sampling of ascites and pleural effusion

Other: Collecting stool samples

Benign controls

Description:

Patients with a benign tumor or an inflammatory disease - to be matched by age.

Treatment:

Other: Collecting saliva sample

Other: Lavage/Irrigation

Other: Tumor tissue collection

Other: Collecting urine samples

Other: Collecting sputum

Other: Sampling of ascites and pleural effusion

Other: Collecting stool samples

Healthy controls

Description:

People/patients who have no known disease at time of sampling or are admitted to the hospital for minor interventions and have no inflammatory disease.

Treatment:

Other: Collecting saliva sample

Other: Lavage/Irrigation

Other: Collecting urine samples

Other: Collecting sputum

Other: Collecting stool samples