Establishment of Ideal IV Sedative Regimen for Successful Fiberoptic Bronchoscopy in Assessing the Site, Severity of Sleep Apnea Syndrome

Yonsei University

Status: Completed

Conditions: Sleep Apnea Syndrome

Treatments: Drug: dexmedetomidine infusion rate, 1.0 mcg/kg/hr; Drug: dexmedetomidine infusion rate, 0.5 mcg/kg/hr

Study type: Interventional

Funder types: Other

Identifiers

NCT02148432

4-2014-0232

Details and patient eligibility

About

Venous thromboembolism(VTE) is the third most common cardiovascular complication among hospitalized patients, and can even cause death. VTE often occurs in intensive care patients and there had been many efforts to prevent such complication. The American College of Chest Physicians (ACCP) had published evidence-based clinical practice guideline for VTE prophylaxis.

This study focuses on how VTE prophylaxis is being performed in both medical and surgical ICUs in a single University hospital, and sees the differences in such prophylactic patterns.

Enrollment: 31 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. 20-60 years old patients with ASA class I-II
2. Scheduled for drug induced sleep endoscope after diagnosed with sleep apnea syndrome

Exclusion criteria

1. Patients having hearing difficulties, taking any CNS related medication, history of any adverse drug reaction, Glasgow coma scale < 15
2. Patients with severe cardiopulmonary dysfunction
3. Patients refusal

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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31 participants in 2 patient groups

dexmedetomidine 0.5 mcg/kg/hr

Experimental group

Treatment:

Drug: dexmedetomidine infusion rate, 0.5 mcg/kg/hr

dexmedetomidine 1.0 mcg/kg/hr

Active Comparator group

Treatment:

Drug: dexmedetomidine infusion rate, 1.0 mcg/kg/hr