Estimating Average Vitamin A Requirements in Indonesian and American Women

University of Wisconsin (UW)

Status: Completed

Conditions: Vitamin A Deficiency

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Vitamin A supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT04123210

A074600 (Other Identifier)

H-2007-0324

AG&LSC/NUTRITIONAL SCI/NUTRITI (Other Identifier)

Details and patient eligibility

About

Women of reproductive age had their vitamin A stores estimated by retinol isotope dilution and then were given vitamin A supplements near the US vitamin A RDA or placebo for 42(USA) or 60 (Indonesia) days, after which retinol isotope dilution was repeated and the change in vitamin A stores was determined in each group to estimate how much vitamin A is needed to maintain nutrient balance in these women.

Enrollment: 70 patients

Sex: Female

Ages: 19 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal nutritional status (BMI 18.5-25)

Exclusion criteria

• Significant clinical illness

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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70 participants in 2 patient groups, including a placebo group

Vitamin A supplement

Experimental group

Description:

Subjects receive a vitamin A supplement containing 175 or 525 micrograms of vitamin A as retinyl palmitate daily

Treatment:

Dietary Supplement: Vitamin A supplement

Placebo

Placebo Comparator group

Description:

Subjects receive an oil placebo containing no vitamin A

Treatment:

Dietary Supplement: Placebo