Estimating Usual Iodine Intake From Spot Urinary Iodine Concentrations (ITURN)

Federal Institute of Technology (ETH) Zurich

Status: Completed

Conditions: Iodine Deficiency

Study type: Observational

Funder types: Other

Identifiers

NCT03602404

ITURN

Details and patient eligibility

About

The overall objective of this study is to develop a reliable method to obtain habitual iodine intakes from spot urinary iodine concentration (UIC) and to assess the prevalence of inadequate iodine intake in school-age children and women of reproductive age. We will evaluate different methods to estimate iodine intake from UIC and estimate the prevalence of inadequate and excess iodine intake in UIC studies conducted in populations with low, adequate and high iodine intakes using the the established estimated average requirement (EAR)/Tolerable Upper Intake Level (UL) cut-point method.

Enrollment: 1,592 patients

Sex: All

Ages: 9 to 13 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• lived in study area >= 12 months
• no reported intake of Amiodarone
• no history of thyroid dysfunction / goiter (past & present)
• no exposure to iodine containing contrast agents within the last 12 months

Second arm: Women aged 18 - 49, exclusion / inclusion criteria apply, plus non-pregnant, non-lactating.

Trial design

1,592 participants in 3 patient groups

St. Petersburg: School aged children

Description:

Generally healthy 9 to 12 years old children

St. Petersburg: Women of reproductive age

Description:

Generally healthy non-pregnant, non-lactating women between 18 and 44 years of age

Papua New Guinea: School aged children

Description:

Generally healthy 9 to 12 years old children