Estimation of Pulmonary Vascular Resistance by Contrast Echocardiography

George Washington University (GW)

Status: Completed

Conditions: Pulmonary Arterial Hypertension

Treatments: Procedure: 2D doppler echo with Definity solution

Study type: Interventional

Funder types: Other

Identifiers

NCT02028299

060922

Details and patient eligibility

About

An echocardiogram using Definity contrast can provide the same information as the standard right heart catheterization.

Enrollment: 38 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients scheduled to undergo right heart catheterization at the George Washington University Hospital

Exclusion criteria

• Patients with known or suspected right-to-left bi-directional or transient right-to-left shunts or pulmonary arteriovenous malformations, previously documented moderate to severe tricuspid regurgitation or moderate to severe pulmonary regurgitation, evidence of right ventricular hypokinesis, or prior adverse reaction to Definity or hypersensitivity to perflutren

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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38 participants in 1 patient group

2D doppler echo with Definity solution

Experimental group

Description:

Study subjects will already be scheduled for right heart catheterization to diagnose pulmonary hypertension. Prior to the catheterization, each subject will have a 2D doppler echocardiogram with Definity solution as well.

Treatment:

Procedure: 2D doppler echo with Definity solution