Estrogen Treatment in Acromegalic Women

Université de Montréal

Status and phase: Unknown; Phase 2

Conditions: Acromegaly

Treatments: Drug: Alesse

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00315107

HND01

Details and patient eligibility

About

Oral estrogens may be an effective adjuvant treatment for control of acromegaly in patients with resistance to somatostatin analogs.

Full description

This will be a canadian multicenter study with a randomized, double-blind, placebo-controlled design, to assess the efficacy and safety of adjuvant alesse in female acromegalic patients with suboptimal response to sandostatin LAR treatment.

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women 18 years and older treated with somatostatin analogs
• Active acromegaly

Exclusion criteria

• Cardiovascular or cerebrovascular disease
• Thrombophlebitis or thromboembolism
• Breast cancer
• Non-controlled arterial hypertension
• Smoking
• Pregnancy or lactation