Etoricoxib vs. Diclofenac in OA (0663-805)(COMPLETED)

Organon

Status and phase

Completed

Phase 3

Conditions

Osteoarthritis

Treatments

Drug: Comparator: diclofenac sodium / Duration of Treatment: 6 Weeks

Drug: MK0663, etoricoxib / Duration of Treatment: 6 Weeks

Study type

Interventional

Funder types

Industry

Identifiers

NCT00542087

0663-805

2007_625

Details and patient eligibility

About

To compare the safety and tolerability of etoricoxib and diclofenac sodium in the treatment of osteoarthritis of the knee or hip during a six week period.

Enrollment

516 patients

Sex

All

Ages

40+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patient is at least 40 years old and diagnosed with osteoarthritis of the knee or hip
Has a history of treatment with NSAIDs with positive therapeutic benefit
Agree to limit alcohol intake to less than 7 drinks per week and avoid unusual strenuous activity
Females who are able to have children must have negative urine pregnancy tests

Exclusion criteria

Has rheumatoid arthritis, lupus, Paget's disease affecting the study joint, or Wilson's disease
History of acute ligament or meniscus damage to the study joint (knee or hip) within the past 2 years or arthroscopic surgery on the affected study joint with the past 6 months
Requires joint replacement