Eustachian Tube Testing in a Pressure Chamber -- Validation Study

University of Pittsburgh

Status: Completed

Conditions: Otitis

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00694486

PRO07070157

1P50DC007667 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study will compare Eustachian tube function (ETF) testing in adults with intact tympanic membranes (TM) using a pressure chamber to that obtained using standard methods requiring a non-intact TM.

Full description

The investigators propose to introduce new test methods and protocols to our laboratory for better clinical characterization of Eustachian tube function in ears with intact TM's. These test will be done in a pressure-chamber and will use previously published and newly developed methods. Participation will require a minimum of 5 visits to the ENT Research Center, 1 for myringotomy (putting a small hole in the eardrum) and 4 for ETF testing. Hearing testing will be done at entry and exit; otoscopy (looking at the ears) and tympanometry (a test done with an earplug and varying pressures in the ear canal) are done at every visit.

Enrollment: 20 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• >18 years old
• Normal middle-ear status

Exclusion criteria

• Chronic illness including asthma, pulmonary, or cardiac problems
• Pregnancy
• >10 dB hearing loss in any of the speech frequencies
• Past history of sensitivity or allergic reaction to lidocaine or related compounds

Trial design

20 participants in 1 patient group

1

Description:

Healthy adult volunteers