Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, Thailand (eCHEC)

McMaster University

Status: Not yet enrolling

Conditions: Liver Fluke-Related Cholangiocarcinoma; Opisthorchiasis; Cholangiocarcinoma

Treatments: Behavioral: eCHEC program

Study type: Interventional

Funder types: Other

Identifiers

NCT05321992

0609004105

13955 (Other Identifier)

Details and patient eligibility

About

Liver cancer, specifically cholangiocarcinoma (CCA), is very common in different areas in Thailand. Many factors make this cancer more common, such as liver fluke infection, older age, eating raw fish, family history of cancer, alcohol intake, taking certain medicines (praziquantel), low intake of fresh vegetable, and low education. In 2015, researchers from Khon Kaen University developed the Community-based Health Education and Communication (CHEC) program to prevent liver cancer caused by liver flukes in communities of the Khon Kaen province, Thailand.

The main aim of this 5-year research study is to enhance the CHEC program to prevent liver cancer, and test if it is effective in improving the knowledge and behaviours of community residents regarding how to prevent liver cancer. This study will take place in Khon Kaen, Thailand. Other aims are to:

1. Increase understanding in the community that make it difficult to prevent liver cancer, as well as community characteristics that can help prevent liver cancer;
2. Incorporate the program we develop in healthcare to prevent liver cancer in Thailand.

Enrollment: 480 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• any individual residing in one of the 16 villages selected in the Khon Kaen province of Thailand, aged 20 and older

Exclusion criteria

• any individual 19 years or younger
• any individual not residing in one of the 16 pre-selected villages in the Khon Kaen province of Thailand

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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480 participants in 2 patient groups

Usual Care Community

No Intervention group

Description:

Participants in this arm will not be given the eCHEC program

eCHEC Community

Active Comparator group

Description:

Participants in this arm will be given the eCHEC program as their intervention

Treatment:

Behavioral: eCHEC program