Evaluating Interventions for Alcohol Use Disorder

Rutgers The State University of New Jersey

Status: Completed

Conditions: Alcoholism

Treatments: Other: IB Assessment; Behavioral: Cognitive Behavioral Therapy; Other: FC Assessment; Behavioral: Motivational Enhancement Therapy

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT02409888

1R01AA022330-01A1 (U.S. NIH Grant/Contract)

Pro2013003944

Details and patient eligibility

About

The purpose of this study is to investigate how behavioral treatments for alcohol use disorders affect behavior change.

Enrollment: 140 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: Study inclusion criteria are such that study participants must:

1. meet a Diagnostic and Statistical Manual-IV (DSM-IV) alcohol abuse or dependence diagnosis based on the Diagnostic Interview Schedule - IV (DIS-IV);
2. consume a weekly average of at least 24 standard drinks during the baseline period to include at least 5 episodes of heavy drinking;
3. agree not to seek additional alcohol or other substance abuse treatment during the study period;
4. be at least 18 years of age; and
5. be sufficiently proficient in their English speaking ability to interact effectively with the research interviewer.

Exclusion Criteria:

• Individuals assessed as having a drug diagnosis that is more severe than their alcohol diagnosis (e.g., cocaine dependence and alcohol abuse, IV drug use),
• a serious psychiatric diagnosis (e.g., uncontrolled schizophrenia or major depression) as well as those meeting criteria for organic brain impairment, as measured by the mini-mental status examination section of the DIS-IV will be precluded from study participation.

In addition,

• individuals reporting current enrollment in a substance abuse treatment program,
• mandated to substance abuse treatment by a court order, or
• severely socially unstable (e.g., homeless) also will be precluded from study participation.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Double Blind

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140 participants in 2 patient groups

Intervention

Experimental group

Description:

Study participants receive either motivational enhancement therapy (MET) or cognitive behavioral therapy (CBT).

Treatment:

Behavioral: Motivational Enhancement Therapy

Behavioral: Cognitive Behavioral Therapy

Assessment

Experimental group

Description:

IB Assessment study participants receive semi-annual assessments specific to their alcohol and other drug use and FC Assessment study participants receive quarterly assessments specific to diverse areas of functioning (e.g., alcohol and other drug use, social, occupational, legal, psychological/psychiatric, marital).

Treatment:

Other: IB Assessment

Other: FC Assessment