Evaluating Microvascular Dysfunction in Symptomatic Patients With HypertroPhic CaRdiomyopathy (PRIMARy)

Lawson Health Research Institute

Status: Completed

Conditions: Hypertrophic Cardiomyopathy

Study type: Observational

Funder types: Other

Identifiers

NCT02994615

108627

Details and patient eligibility

About

Patients with hypertrophic cardiomyopathy are being compared to a control group. IMR will be assessed with a pressure wire. Clinical f/u at 3 months and 6 months and a 48 hour holter monitor.

Enrollment: 19 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-80
• Already have an indication for coronary angiography
• Previous diagnosis of hypertrophic cardiomyopathy (unless control)

Exclusion criteria

• Fractional flow reserve found to be significant (FFR < 0.8)
• Already have a condition associated with or likely to be associated with an elevated IMR (diabetes, cardiac syndrome X, takotsubo cardiomyopathy, hypertensive cardiomyopathy, severe aortic stenosis, STEMI)

Trial design

19 participants in 2 patient groups

hypertrophic cardiomyopathy

Control