Evaluating Radiomorphometric Indices and Fractal Dimension of the Pediatric Oncology Patients on Panoramic Images

Nuh Naci Yazgan University

Status: Completed

Conditions: Oncology; Bone Loss

Treatments: Radiation: Panoramic Radiography

Study type: Observational

Funder types: Other

Identifiers

NCT04213482

2018/209

Details and patient eligibility

About

This study evaluated pediatric oncology patients in terms of quality of bone and determine any relation between bone quality and radiotherapy/chemotherapy. The alternative hypothesis is that the bone quality of the oncology patients who received radiotherapy/chemotherapy is lower than the control group.

Full description

Cancer is the abnormal and uncontrolled proliferation of certain tissues in the body for a reason that cannot be determined yet. Childhood cancers occur between 0-17 years of age, and follow-up and treatment of these patients are performed in pediatric oncology services. Diagnosis in childhood cancers can be made by clinical examination as well as blood tests and examination of tissue samples. There are also some imaging methods used for diagnosis; ultrasonography, computed tomography, magnetic resonance imaging, positron emission tomography / computed tomography (PET / CT).

Treatment methods in childhood cancers are as follows; surgery, chemotherapy, radiotherapy and stem cell transplantation. Once diagnosed, oncologists and surgeons may choose one of these treatment options by mutual consultation or decide on a treatment method. Fractal analysis is a numerical as fractal dimension. Trabeculae are thin columns with numerous large spaces that give a honeycomb or spongy appearance of cancellous bone, which is also called trabecular bone or spongy bone. Previously, fractal analysis has been reported as a useful method to detect various diseases that affect the trabecular bone structure. Particularly in the field of dentistry, studies have shown that fractal analysis by the box-counting method can successfully evaluate trabecular changes in the mandible of patients with osteoporosis and periodontal diseases and in lactating women.

Enrollment: 100 patients

Sex: All

Ages: 6 to 23 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• to have been treated for any oncological diseases in childhood
• oncological treatment completed at least one year ago

Exclusion criteria

• ongoing oncological treatment
• patients who unwilling to participate to study

Trial design

100 participants in 2 patient groups

oncology patients

Description:

For this study, panoramic images were taken from pediatric patients who received radiotherapy and/or chemotherapy because of any oncologic disease.

Treatment:

Radiation: Panoramic Radiography

healthy

Description:

panoramic images of patients(pediatric) who have no systemic disease were collected from the archive of dental radiology clinic of the university hospital.

Treatment:

Radiation: Panoramic Radiography