Evaluating Rewards-Based Adherence and Electronic Medication Monitoring in HIV-Positive Adolescents

St. Jude Children's Research Hospital

Status: Completed

Conditions: Human Immunodeficiency Virus (HIV); Acquired Immunodeficiency Syndrome (AIDS)

Treatments: Other: Questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT01849393

INTECH

Details and patient eligibility

About

The primary objective of this project is to assess the study population's acceptance of two medication adherence support strategies: incentive-based programs and electronic medication monitoring. The study population is adolescents (ages 16 - 24) positive for human immunodeficiency virus (HIV) currently undergoing treatment with antiretrovirals at St. Jude's HIV clinic. Participation in the study will involve completion of a survey: an Audio Computer Assisted Self Interview (ACASI). The duration of the survey is anticipated to be 10-20 minutes. Patient identifiers will not be attached the survey.

Full description

Whether or not patients take their medications is one of the most noticeable and important predictors of treatment success or failure for HIV infection. Ways to improve compliance, specifically rewards-based programs and electronic medication monitoring, have shown some success in limited clinical research studies focused on adult subjects. Because the social and developmental factors in adolescents are different from adults, adolescents may not respond to these interventions in the same way as adults. This study will investigate adolescent acceptance and the effectiveness of these programs.

Enrollment: 100 patients

Sex: All

Ages: 16 to 24 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV positive
• Ages 16-24 years.
• Participants must understand written or spoken English, because the ACASI used in the study can only be administered in English.

Exclusion criteria

• Adolescents with a documented diagnosis of mental retardation or a significant motor or sensory impairment that would preclude participation in the study survey.

Trial design

100 participants in 1 patient group

Study Population

Description:

Participants must meet the eligibility requirements will complete a questionnaire on the computer.

Treatment:

Other: Questionnaire