Evaluating the Efficacy of Current Treatments for Reducing Postoperative Ileus

Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo

Status: Completed

Conditions: Post-operative Ileus

Treatments: Dietary Supplement: olive oil and chewing gum; Dietary Supplement: water; Dietary Supplement: chewing gum; Dietary Supplement: olive oil

Study type: Interventional

Funder types: Other

Identifiers

NCT01869231

17070401

Details and patient eligibility

About

Aim was to investigate efficacy of current treatments - water, chewing gum, and olive oil, in resolving postoperative ileus.

Enrollment: 360 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients underwent abdominal surgery for non neoplastic diseases

Exclusion criteria

• Metastatic disease
• History of inflammatory bowel disease
• Postoperative fever
• Gastrointestinal fistula
• Mint or olive allergy; and/or
• Earlier abdominal radiation

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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360 participants in 4 patient groups

major surgery

Experimental group

Description:

colic surgery

Treatment:

Dietary Supplement: olive oil

Dietary Supplement: water

Dietary Supplement: chewing gum

Dietary Supplement: olive oil and chewing gum

minor surgery

Experimental group

Description:

appendectomy; cholecystectomy

Treatment:

Dietary Supplement: olive oil

Dietary Supplement: water

Dietary Supplement: chewing gum

Dietary Supplement: olive oil and chewing gum

ileostomy and colostomy

Experimental group

Description:

ileostomy colostomy

Treatment:

Dietary Supplement: olive oil

Dietary Supplement: water

Dietary Supplement: chewing gum

Dietary Supplement: olive oil and chewing gum

other surgery

Experimental group

Description:

all of others abdominal surgical intervention

Treatment:

Dietary Supplement: olive oil

Dietary Supplement: water

Dietary Supplement: chewing gum

Dietary Supplement: olive oil and chewing gum