Evaluating the Feasibility of Disseminating a Novel Mobile Platform to Treat Depression (PRIME-D)

University of California San Francisco (UCSF)

Status: Withdrawn

Conditions: Depression

Treatments: Behavioral: PRIME 1.0; Behavioral: PRIME 2.0

Study type: Interventional

Funder types: Other

Identifiers

NCT02817672

1R34MH110583-01

Details and patient eligibility

About

The goal of this project is to conduct a pilot study to test the utility of a Natural Language Processing (NLP) clinical messaging tool to improve the reach and the quality (fidelity and competency) of coaches providing behavioral activation (BA) strategies through a mobile mental health app called Personalized Real-time Intervention for Motivational Enhancement (PRIME). This study will improve the reach of clinicians by using a NLP-powered messaging tool, which will ensure fidelity to the BA model and clinicians will have access to real-time clinical information about their patients to guide more targeted treatment (competence). If successful, PRIME could operate as a cost effective tool for clinicians to extend their reach and an accessible treatment for the population of those struggling with depression.

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 and older
• Read and speak English
• PHQ-9 score of 5 or greater or indicate that their depressive symptoms are interfering with their daily functioning (Item 10 of the PHQ-9 > 2).
• To be consistent with the NIMH RDoC initiative, we will assess for co-morbid problems (substance abuse, anxiety, and psychosis), but will not exclude participants with psychiatric comorbidities
• Must own a mobile device on iOS or Android platforms that either Wi-Fi or 3G/4G ready;

Exclusion criteria

• Under 18
• Cannot read or speak in English
• Cannot attain suitable mobile device

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

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0 participants in 2 patient groups

PRIME 1.0

Active Comparator group

Description:

8 weeks use of PRIME 1.0 (current version). Mobile application designed to improve psychosocial functioning and motivational deficits.

Treatment:

Behavioral: PRIME 1.0

PRIME 2.0

Experimental group

Description:

8 weeks use of PRIME 2.0 (version with the NLP-powered dashboard). Mobile application designed to improve psychosocial functioning and motivational deficits.

Treatment:

Behavioral: PRIME 2.0