Evaluating the Influence of Apnea on Cardiac Function Using Cardiac Magnetic Resonance Imaging.

University Hospital Bonn (UKB)

Status: Completed

Conditions: Physiological Changes in Deliberate Apnea

Treatments: Device: magnetic resonance imaging (MRI)

Study type: Interventional

Funder types: Other

Identifiers

NCT02280226

UBonn-MRI-heart-14

Details and patient eligibility

About

Former studies revealed a distinct pattern of changes in circulation during deliberate apnea. Blood pressure rises significantly often accompanied by bradycardia. Further studies confirmed a massive increase of total vascular resistance as it also happens in shock to maintain perfusion of heart, lung and brain. This study is to determine the exact alterations of the cardiac function during this reaction, show the redistribution of blood volume in apnea and evaluate possible longterm effects on the central nervous system caused by repeated apnea via magnetic resonance imaging.

Enrollment: 17 patients

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Being able to hold breath deliberately at least 4,5 minutes

Exclusion criteria

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

17 participants in 1 patient group

Deliberate Apnea Group

Experimental group

Description:

Subjects undergo maximum apnea.

Treatment:

Device: magnetic resonance imaging (MRI)