Evaluating the Patient-Ventilator Synchrony During Mechanical Ventilation in Patients With Acute Lung Injury

The University of Chicago

Status: Completed

Conditions: Mechanically Ventilated ICU Patients

Study type: Observational

Funder types: Other

Identifiers

NCT01541514

11-0172

Details and patient eligibility

About

The overall purpose to the study is to prospectively study how often patients with and without acute lung injury (ALI) have patient-ventilator asynchrony demonstrated as stacked breaths. The investigators seek to describe the quantity of stacked breaths by continuously recording flow, volume, and pressure waveforms routinely displayed on the vent. The investigators also seek to describe how primary ICU teams manage asynchrony documenting interventions of sedation or vent manipulation and what modality is most successful.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

age > 18 years intubated and mechanically ventilated diagnosed with acute lung injury (ALI) or requiring mechanical ventilation for reasons other than ALI

Exclusion criteria

neurological deficits (acute or chronic) that prevent effective diaphragm activity.

• Neuromuscular disease affecting the diaphragm
• Neuromuscular blockade