Evaluating the Unmet Needs of Older Adults to Promote Functional Recovery After a Critical Illness (LANTERN)

Yale University

Status

Enrolling

Conditions

Critical Illness

Illness, Critical

Study type

Observational

Funder types

Other

NIH

Identifiers

NCT06006000

2000034943

1R01AG079916-01A1 (Other Grant/Funding Number)

Details and patient eligibility

About

This is a prospective longitudinal study that will evaluate the unmet needs of older adults (65 and older) who return home (either directly or after short-term rehab) after an ICU hospitalization, evaluate the association of these unmet needs with clinically relevant outcomes, and assess barriers and facilitators to addressing these unmet needs. The proposed research will inform the development and evaluation of a subsequent intervention to improve functional outcomes among older ICU survivors, in alignment with the NIH's mission to reduce disability.

Full description

To identify unmet needs in multiple domains after return home from an ICU hospitalization, evaluate whether these unmet needs are associated with disability burden in the subsequent 6 months, and ascertain whether these associations are moderated by initial discharge destination (home or STR).

Enrollment

650 estimated patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

PARTICIPANTS

Age ≥ 65 years
Survived an ICU admission of ≥2 days

CAREGIVERS

Age ≥ 18 years
Identified as caregiver of LANTERN participant who is an informal (unpaid) caregiver.

Exclusion criteria

PARTICIPANTS

Advance directive of comfort measures only (CMO) or a transition to hospice
Planned discharge to a location other than home or Short-Term Rehab
Tracheostomy with ventilator dependence
Severe acute or prior neurologic injury (such as anoxic brain injury or acute, massive stroke)
Advanced dementia
ICU admission for monitoring only (e.g., antibiotic desensitization)
Primary language other than English.
Homelessness
Active drug or alcohol use disorder.

CAREGIVERS